Time: 12.30 – 1.30
Speaker: Dr Sandra Vranic – Associate Professor and Nano-Cell Biology Group Leader, The University of Manchester
Title: Graphene-enabled enzyme delivery for lysosomal storage disorders: towards more effective therapies for rare conditions
Abstract: Sandra Vranic, PhD, is Associate Professor in Nano-Cell Biology at The University of Manchester, where she leads the Nano-Cell Biology Group, serves as Programme Director for the MSc in Nanomedicine, and is Technology Platform Lead at the Henry Royce Institute. Her research focuses on the use of advanced human in vitro models in nanomedicine and nanotoxicology, as well as on translational strategies to improve treatment delivery in complex diseases. Her talk will highlight the use of graphene flakes as versatile carriers for lysosomal enzymes, with recent findings demonstrating preserved enzyme activity after complexation with the material, successful application across multiple patient-derived fibroblast models, and gradual intracellular clearance over time.
